What is the major function of T regulatory cells?

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Study for the Stevens Immunology-Serology Test. Explore flashcards and multiple choice questions with detailed explanations and hints. Get exam ready now!

Multiple Choice

What is the major function of T regulatory cells?

Explanation:
Regulatory T cells act to keep the immune system in check by suppressing responses and maintaining tolerance. A key way they do this is by releasing anti-inflammatory signals, especially IL-10, which dampens the activity of effector T cells and other immune cells like macrophages. This suppressive function helps prevent autoimmunity and limit excessive inflammation. The other options describe promoting or proliferating immune responses: TNF drives inflammation, while IL-2 and IL-4 promote T cell proliferation and differentiation.

Regulatory T cells act to keep the immune system in check by suppressing responses and maintaining tolerance. A key way they do this is by releasing anti-inflammatory signals, especially IL-10, which dampens the activity of effector T cells and other immune cells like macrophages. This suppressive function helps prevent autoimmunity and limit excessive inflammation. The other options describe promoting or proliferating immune responses: TNF drives inflammation, while IL-2 and IL-4 promote T cell proliferation and differentiation.

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